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rabbit polyclonal anti human k ca 2 3  (Alomone Labs)


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    Alomone Labs rabbit polyclonal anti human k ca 2 3
    K + channel expression and hyperpolarization to bradykinin in human and porcine IMCAs. Confocal micrographs of immunolabelling for K Ca 3.1 and K Ca 2.3 in isolated, cannulated and pressurized human (A) and porcine (B) RA-IMCAs with myogenic tone and full dilation to BK. Punctate and diffuse K Ca 3.1 label was evident in the ECs of human and porcine arteries, whereas K Ca 2.3 was less clear in human IMCAs, and highly expressed at EC borders of porcine IMCAs (yellow arrowheads). The elastin was dense in human arteries, with the internal elastic lamina (IEL) seen as longitudinal strings in the porcine arteries. Representative of at least 3 arteries for each label; asterisks indicate corresponding nuclei in upper and lower panels. The pink dashed line in the schematic represents the focal plane. (C) The schematic indicates a sharp microelectrode impaled into a SMC of a porcine RA-IMCA mounted for isometric tension recording. Under control conditions the thromboxane mimetic U46619 (0.6 μM) depolarized and contracted arteries, and BK (10 nM) caused hyperpolarization and relaxation (C) , summarized in (D) . (E) Addition of L-NAME depolarized and contracted porcine left ventricular (LV)-IMCAs. Under these conditions BK (0.1 nM to 100 nM) repolarized and relaxed the artery. Addition of 100 nM acetylcholine (ACh) depolarized and contracted the artery. The asterisk indicates when the electrode came out of the cell. The RMP and tension prior to the addition of L-NAME (100 μM) are indicated by dashed lines. Drugs were added to a static bath at the arrows. RMP, resting membrane potential.
    Rabbit Polyclonal Anti Human K Ca 2 3, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 95/100, based on 79 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rabbit+polyclonal+anti+human+kca2+3/pmc09411971-141-32-40?v=Alomone+Labs
    Average 95 stars, based on 79 article reviews
    rabbit polyclonal anti human k ca 2 3 - by Bioz Stars, 2026-07
    95/100 stars

    Images

    1) Product Images from "Signaling and structures underpinning conducted vasodilation in human and porcine intramyocardial coronary arteries"

    Article Title: Signaling and structures underpinning conducted vasodilation in human and porcine intramyocardial coronary arteries

    Journal: Frontiers in Cardiovascular Medicine

    doi: 10.3389/fcvm.2022.980628

    K + channel expression and hyperpolarization to bradykinin in human and porcine IMCAs. Confocal micrographs of immunolabelling for K Ca 3.1 and K Ca 2.3 in isolated, cannulated and pressurized human (A) and porcine (B) RA-IMCAs with myogenic tone and full dilation to BK. Punctate and diffuse K Ca 3.1 label was evident in the ECs of human and porcine arteries, whereas K Ca 2.3 was less clear in human IMCAs, and highly expressed at EC borders of porcine IMCAs (yellow arrowheads). The elastin was dense in human arteries, with the internal elastic lamina (IEL) seen as longitudinal strings in the porcine arteries. Representative of at least 3 arteries for each label; asterisks indicate corresponding nuclei in upper and lower panels. The pink dashed line in the schematic represents the focal plane. (C) The schematic indicates a sharp microelectrode impaled into a SMC of a porcine RA-IMCA mounted for isometric tension recording. Under control conditions the thromboxane mimetic U46619 (0.6 μM) depolarized and contracted arteries, and BK (10 nM) caused hyperpolarization and relaxation (C) , summarized in (D) . (E) Addition of L-NAME depolarized and contracted porcine left ventricular (LV)-IMCAs. Under these conditions BK (0.1 nM to 100 nM) repolarized and relaxed the artery. Addition of 100 nM acetylcholine (ACh) depolarized and contracted the artery. The asterisk indicates when the electrode came out of the cell. The RMP and tension prior to the addition of L-NAME (100 μM) are indicated by dashed lines. Drugs were added to a static bath at the arrows. RMP, resting membrane potential.
    Figure Legend Snippet: K + channel expression and hyperpolarization to bradykinin in human and porcine IMCAs. Confocal micrographs of immunolabelling for K Ca 3.1 and K Ca 2.3 in isolated, cannulated and pressurized human (A) and porcine (B) RA-IMCAs with myogenic tone and full dilation to BK. Punctate and diffuse K Ca 3.1 label was evident in the ECs of human and porcine arteries, whereas K Ca 2.3 was less clear in human IMCAs, and highly expressed at EC borders of porcine IMCAs (yellow arrowheads). The elastin was dense in human arteries, with the internal elastic lamina (IEL) seen as longitudinal strings in the porcine arteries. Representative of at least 3 arteries for each label; asterisks indicate corresponding nuclei in upper and lower panels. The pink dashed line in the schematic represents the focal plane. (C) The schematic indicates a sharp microelectrode impaled into a SMC of a porcine RA-IMCA mounted for isometric tension recording. Under control conditions the thromboxane mimetic U46619 (0.6 μM) depolarized and contracted arteries, and BK (10 nM) caused hyperpolarization and relaxation (C) , summarized in (D) . (E) Addition of L-NAME depolarized and contracted porcine left ventricular (LV)-IMCAs. Under these conditions BK (0.1 nM to 100 nM) repolarized and relaxed the artery. Addition of 100 nM acetylcholine (ACh) depolarized and contracted the artery. The asterisk indicates when the electrode came out of the cell. The RMP and tension prior to the addition of L-NAME (100 μM) are indicated by dashed lines. Drugs were added to a static bath at the arrows. RMP, resting membrane potential.

    Techniques Used: Expressing, Isolation



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    rabbit polyclonal anti human k ca 2 3  (Alomone Labs)
    95
    Alomone Labs rabbit polyclonal anti human k ca 2 3
    K + channel expression and hyperpolarization to bradykinin in human and porcine IMCAs. Confocal micrographs of immunolabelling for K Ca 3.1 and K Ca 2.3 in isolated, cannulated and pressurized human (A) and porcine (B) RA-IMCAs with myogenic tone and full dilation to BK. Punctate and diffuse K Ca 3.1 label was evident in the ECs of human and porcine arteries, whereas K Ca 2.3 was less clear in human IMCAs, and highly expressed at EC borders of porcine IMCAs (yellow arrowheads). The elastin was dense in human arteries, with the internal elastic lamina (IEL) seen as longitudinal strings in the porcine arteries. Representative of at least 3 arteries for each label; asterisks indicate corresponding nuclei in upper and lower panels. The pink dashed line in the schematic represents the focal plane. (C) The schematic indicates a sharp microelectrode impaled into a SMC of a porcine RA-IMCA mounted for isometric tension recording. Under control conditions the thromboxane mimetic U46619 (0.6 μM) depolarized and contracted arteries, and BK (10 nM) caused hyperpolarization and relaxation (C) , summarized in (D) . (E) Addition of L-NAME depolarized and contracted porcine left ventricular (LV)-IMCAs. Under these conditions BK (0.1 nM to 100 nM) repolarized and relaxed the artery. Addition of 100 nM acetylcholine (ACh) depolarized and contracted the artery. The asterisk indicates when the electrode came out of the cell. The RMP and tension prior to the addition of L-NAME (100 μM) are indicated by dashed lines. Drugs were added to a static bath at the arrows. RMP, resting membrane potential.
    Rabbit Polyclonal Anti Human K Ca 2 3, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rabbit+polyclonal+anti+human+kca2+3/pmc09411971-141-32-40?v=Alomone+Labs
    Average 95 stars, based on 1 article reviews
    rabbit polyclonal anti human k ca 2 3 - by Bioz Stars, 2026-07
    95/100 stars
    		  Buy from Supplier
    rabbit polyclonal anti human kca2 3  (Alomone Labs)
    95
    Alomone Labs rabbit polyclonal anti human kca2 3
    K + channel expression and hyperpolarization to bradykinin in human and porcine IMCAs. Confocal micrographs of immunolabelling for K Ca 3.1 and K Ca 2.3 in isolated, cannulated and pressurized human (A) and porcine (B) RA-IMCAs with myogenic tone and full dilation to BK. Punctate and diffuse K Ca 3.1 label was evident in the ECs of human and porcine arteries, whereas K Ca 2.3 was less clear in human IMCAs, and highly expressed at EC borders of porcine IMCAs (yellow arrowheads). The elastin was dense in human arteries, with the internal elastic lamina (IEL) seen as longitudinal strings in the porcine arteries. Representative of at least 3 arteries for each label; asterisks indicate corresponding nuclei in upper and lower panels. The pink dashed line in the schematic represents the focal plane. (C) The schematic indicates a sharp microelectrode impaled into a SMC of a porcine RA-IMCA mounted for isometric tension recording. Under control conditions the thromboxane mimetic U46619 (0.6 μM) depolarized and contracted arteries, and BK (10 nM) caused hyperpolarization and relaxation (C) , summarized in (D) . (E) Addition of L-NAME depolarized and contracted porcine left ventricular (LV)-IMCAs. Under these conditions BK (0.1 nM to 100 nM) repolarized and relaxed the artery. Addition of 100 nM acetylcholine (ACh) depolarized and contracted the artery. The asterisk indicates when the electrode came out of the cell. The RMP and tension prior to the addition of L-NAME (100 μM) are indicated by dashed lines. Drugs were added to a static bath at the arrows. RMP, resting membrane potential.
    Rabbit Polyclonal Anti Human Kca2 3, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rabbit+polyclonal+anti+human+kca2+3/pm36035957-127-28-34?v=Alomone+Labs
    Average 95 stars, based on 1 article reviews
    rabbit polyclonal anti human kca2 3 - by Bioz Stars, 2026-07
    95/100 stars
    		  Buy from Supplier

    Image Search Results


    K + channel expression and hyperpolarization to bradykinin in human and porcine IMCAs. Confocal micrographs of immunolabelling for K Ca 3.1 and K Ca 2.3 in isolated, cannulated and pressurized human (A) and porcine (B) RA-IMCAs with myogenic tone and full dilation to BK. Punctate and diffuse K Ca 3.1 label was evident in the ECs of human and porcine arteries, whereas K Ca 2.3 was less clear in human IMCAs, and highly expressed at EC borders of porcine IMCAs (yellow arrowheads). The elastin was dense in human arteries, with the internal elastic lamina (IEL) seen as longitudinal strings in the porcine arteries. Representative of at least 3 arteries for each label; asterisks indicate corresponding nuclei in upper and lower panels. The pink dashed line in the schematic represents the focal plane. (C) The schematic indicates a sharp microelectrode impaled into a SMC of a porcine RA-IMCA mounted for isometric tension recording. Under control conditions the thromboxane mimetic U46619 (0.6 μM) depolarized and contracted arteries, and BK (10 nM) caused hyperpolarization and relaxation (C) , summarized in (D) . (E) Addition of L-NAME depolarized and contracted porcine left ventricular (LV)-IMCAs. Under these conditions BK (0.1 nM to 100 nM) repolarized and relaxed the artery. Addition of 100 nM acetylcholine (ACh) depolarized and contracted the artery. The asterisk indicates when the electrode came out of the cell. The RMP and tension prior to the addition of L-NAME (100 μM) are indicated by dashed lines. Drugs were added to a static bath at the arrows. RMP, resting membrane potential.

    Journal: Frontiers in Cardiovascular Medicine

    Article Title: Signaling and structures underpinning conducted vasodilation in human and porcine intramyocardial coronary arteries

    doi: 10.3389/fcvm.2022.980628

    Figure Lengend Snippet: K + channel expression and hyperpolarization to bradykinin in human and porcine IMCAs. Confocal micrographs of immunolabelling for K Ca 3.1 and K Ca 2.3 in isolated, cannulated and pressurized human (A) and porcine (B) RA-IMCAs with myogenic tone and full dilation to BK. Punctate and diffuse K Ca 3.1 label was evident in the ECs of human and porcine arteries, whereas K Ca 2.3 was less clear in human IMCAs, and highly expressed at EC borders of porcine IMCAs (yellow arrowheads). The elastin was dense in human arteries, with the internal elastic lamina (IEL) seen as longitudinal strings in the porcine arteries. Representative of at least 3 arteries for each label; asterisks indicate corresponding nuclei in upper and lower panels. The pink dashed line in the schematic represents the focal plane. (C) The schematic indicates a sharp microelectrode impaled into a SMC of a porcine RA-IMCA mounted for isometric tension recording. Under control conditions the thromboxane mimetic U46619 (0.6 μM) depolarized and contracted arteries, and BK (10 nM) caused hyperpolarization and relaxation (C) , summarized in (D) . (E) Addition of L-NAME depolarized and contracted porcine left ventricular (LV)-IMCAs. Under these conditions BK (0.1 nM to 100 nM) repolarized and relaxed the artery. Addition of 100 nM acetylcholine (ACh) depolarized and contracted the artery. The asterisk indicates when the electrode came out of the cell. The RMP and tension prior to the addition of L-NAME (100 μM) are indicated by dashed lines. Drugs were added to a static bath at the arrows. RMP, resting membrane potential.

    Article Snippet: Primary antibodies were as follows: 1:100 rabbit polyclonal anti-rat K Ca 3.1 (aa 350–363; Alomone Laboratories, APC-064); 1:100 mouse monoclonal anti-human K Ca 3.1 (third extracellular loop; Alomone Laboratories, ALM-051); and 1:100 rabbit polyclonal anti-human K Ca 2.3 (aa 2–21, Alomone Laboratories, APC-025).

    Techniques: Expressing, Isolation